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The majority of published studies on the effects of pesticides on human health have focused on cancer, although numerous studies do not support this view. A positive association between exposure to pesticides and some types of cancer has been established, but the results for other cancers are inconclusive. Epigenetic changes resulting from pesticide exposure also have been linked to cancer development. The magnitude and duration of exposure is critical for the health effects, and few studies have focused on this aspect of risk assessment.
The relative risk is the most important parameter and there is no direct relationship between this risk and the concentration of the chemical measured in the environment.
Furthermore, there are probably threshold effects for various classes of pesticides, and effects are only observed at extremely high concentrations. There are many indirect effects of pesticides on the environment that can contribute to their overall toxicity, and these mechanisms cannot be considered part of the risk assessment…. When the latest generation Mac was released, Apple encouraged applications to be updated for the new operating system.
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